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The fasted state is criticalinsulin suppresses NNMT activity, so dosing during fed states reduces 5-Amino-1MQ's efficacy
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Some researchers have suggested that these promising results warrant further research to study the compounds potential benefits for metabolic conditions like type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD) [5]
Recently, NNMT has been emerging as a new mechanism-of-action target for treatment of obesity and associated T2D [10]
