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Dihexa can often be safely combined with other cognitive enhancement therapies including omega-3 fatty acids, B-vitamins, nootropic supplements like Lions Mane or Bacopa monnieri, acetylcholine precursors, and brain-supporting nutrients when properly coordinated under medical supervision

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Taken together, these data suggest that inhibiting HGF does not alter the number of functional synapses in vehicle treated neurons but attenuates the effects of HGF and Dihexa on synaptogenesis by decreasing the number of postsynaptic spines