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Immune cells, including lymphocytes, macrophages, and neutrophils, rely heavily on glutamine as an energy source and a precursor for nucleotide synthesis, which is essential for cell proliferation

FIGURE 1 Anti-inflammatory mechanisms Curcumin demonstrates its anti-inflammatory properties by engaging with important receptors and altering various inflammatory signaling pathways

Patients with severe COVID-19 have elevated levels of high mobility group box 1, 144 a potential biomarker of sepsis that is modulated by NFB

2.11 Statistical analysis The results are presented as the mean standard deviation (SD), calculated from a minimum of three independent experiments