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287 Multiple sclerosis Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease with antibodies primarily attacking myelin sheaths and causing multiple demyelinated areas in white and grey matter throughout the CNS (with most frequent localisation in the optic nerve, spinal cord, brain stem, periventricular white matter, and the grey matter near the subarachnoid space)

Its B ring displays the catechol portion and multiple free hydroxyl groups that drive the reduction of Fe 3+ to Fe 2+ (73)

Trimethylamine-N-Oxide promotes age-related vascular oxidative stress and endothelial dysfunction in mice and healthy humans

Gynecol Reprod Endocrinol Metab