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doi: 10.7150/thno.39566
Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses

The gastric mucosa is a specialized epithelial layer that depends on continuous ECM remodeling and collagen synthesis for structural integrity
In the unlikely event of significant copper toxicity, treatment involves IV chelation therapy using EDTA, which binds to excess copper and allows it to be excreted through the kidneys
