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doi: 10.1016/j.brs.2019.05.002 33 WangLGaoFWangZLiangFDaiYWangMet al
part of the electromagnetic spectrum with wavelengths from 100 nm - 400 nm UV-A Ultraviolet radiation with longer wavelengths (315-400 nm) UV-B Ultraviolet radiation with shorter wavelengths (280-315 nm) AP-1 Activator protein 1

Canonical Smad2/3 signaling is a well-established mechanism of TGF--driven extracellular-matrix (ECM) synthesis
They eventually showed it was effective for various forms of hyperpigmentation, including melasma and post-inflammatory hyperpigmentation
