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So far, 13 variants of human GR exon 1 differing in the upstream promoter regions have been characterized

This BCAC increases the activation of cytoplasmic phospholipase A2 (cPLA2) by binding to integrin 21 in platelets and promoting platelet hyperresponsiveness, thus promoting thrombosis [239]
With advancements in multiomics technologies, integrated analyses combining metagenomics, metabolomics, and clinical phenomics of gut microbiota characteristics, microbial metabolites, and clinical features of patients offer a novel perspective for outcome prediction