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It suggests that because Nrf2 can modulate the detoxification pathways, its effect on anticancer drugs may lead to chemoresistance and that the switch between a beneficial and a detrimental role for Nrf2 in cancer cells depends on a number of factors which include the tight control of its activity
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doi: 10.3390/molecules20034813
Researchers commonly utilise MT-2 in broader in-vitro studies involving receptor-related signalling models and peptide stability investigations
