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de Angelis C, Galdiero M, Pivonello C et al (2017) The environment and male reproduction: The effect of cadmium exposure on reproductive function and its implication in fertility

In other words: if a researcher is studying IGF-1 LR3's effects on cell proliferation and the preparation is contaminated with endotoxin, the observed proliferation response could be driven by LPS rather than by IGF-1 LR3 signaling through IGF-1R
& Zhang, J
The puffy look associated with aging diminishes, revealing a sharper, more defined physique
