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As antidiabetic drugs like insulin can regulate lipid metabolism, they have been explored in preclinical and clinical studies for PD

They are rapidly converted to thiamine in the cell by enzymatic or nonenzymatic processes [4]

doi: 10.1016/j.semcdb.2005.03.010 132 SenaLALiSJairamanAPrakriyaMEzpondaTHildemanDAet al

PBMC from unrelated healthy individuals were used as controls (CTRL: C1 to C5)
