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Description
By blocking NNMT, it prevents the methylation reaction that depletes SAM and nicotinamide, thereby preserving both cofactors and restoring the metabolic machinery that NNMT overexpression had suppressed
"Trends in blood folate and vitamin B-12 concentrations in the United States, 1988 2004"

doi:10.1097/md.0000000000004495 Stevens H, McFadyen JD

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