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Moreover, the conditioned medium of CRP-overexpressing HepG2 cells increased the release of these cytokines from RAW264.7 cells to a greater degree than recombinant CRP

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doi: 10.3389/fmicb.2022.814855

Pregnancy Melasma Hyperpigmentation occurs in ~85%90% of pregnant women, appears to be associated, at least in part, with increased expression and/or signalling of MC1R, and typically resolves postpartum
