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In children, accidental ingestion should be regarded as serious

The ARE activation can initiate the transcription of downstream antioxidant protective genes and phase II detoxification enzyme genes, which translates into HO-1, superoxide dismutase (SOD), NQO1, catalase, glutathione peroxidase, glutamate-cysteine ligase, glutathione-S-transferase and epoxide hydrolase, etc

Glutamate homeostasis, supported by astrocytes, is of particular relevance
