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Description
Since S is natively an IDP in solution, bearing little to no ordered structure, rational design of compounds to stabilise the monomeric, non-toxic conformation is difficult

Nonapoptotic and extracellular activity of granzyme B mediates resistance to regulatory T cell (Treg) suppression by HLA-DR-CD25hiCD127lo Tregs in multiple sclerosis and in response to IL-6

Quality control checkpoints and batch documentation help ensure consistent product properties

mechanistic and exploratory, not a clinical efficacy trial
