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To understand if treatment with a GPX4 inhibitor was able to eliminate senescent cells in vivo, we treated mice transduced with an NRAS G12V -expressing transposon with RSL3 (Fig

TRP is a precursor for synthesizing the neurotransmitter serotonin and many immunoregulatory and neuroactive kynurenines that control energy homeostasis and modulate behavior

Studies showthat patients with periodontitis show apparently boosted production of oxygen free radicals, possibly leading to lipid peroxidation, DNA damage, and protein oxidation, worsening tissue damage and inflammatory responses (Varela-Lpez et al., 2018)

Determination of the extent of similarity in their transcriptional programs might provide more information about the design of mouse models for FSHD [28]