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As other members of the SLC22 family, OCTN2 can mediate cellular uptake of oxaliplatin and other chemotherapeutic agents (Jong et al., 2011
doi:10.1016/j.jphs.2021.01.010

with no cause identified) (Punab et al

Indeed, an increased oxidative stress is often found in patients with valvular heart diseases, including MR (29)
