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However, HMGB1 secretion during cervical cancer progression impairs the antiviral response by inhibiting IFN secretion and increasing ICOSL (Inducible T Cell Costimulator Ligand) expression by plasmacytoid dendritic cells (pDCs)

for personal research purposes but not for medical prescription

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Its dysfunction leads to GSH depletion, rendering GPX4 unable to effectively exert its antioxidant function even with adequate expression (Wu et al., 2025a
