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Description
Mitochondrial modulators in the treatment of bipolar depression: a systematic review and meta-analysis
Ain Shams Univ
In reaction order these enzymes are GTP cyclohydrolase 1 (GTPCH), 6-pyruvoyltetrahydropterin synthase (PTPS), and sepiapterin reductase (SR)

The PANTHER trial (IPFnet) compared NAC, combination therapy (prednisone + azathioprine + NAC), and placebo in 236 patients (138)
