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Under physiological conditions, nutrient deprivation or oxidative stress activates the unc-51 like autophagy activating kinase 1 (ULK1) kinase complex by inhibiting mTORC1, initiating autophagosome nucleation [151]

doi: 10.1167/iovs.63.3.30 112 HillCGuarnerFReidGGibsonGRMerensteinDJPotBet al

Cells 8 , 984 (2019)

Antioxid Redox Signal 11:271739 Siems W, Crifo C, Capuozzo E, Uchida K, Grune T, Salerno C (2010) Metabolism of 4-hydroxy-2-nonenal in human polymorphonuclear leukocytes
