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Each method has its own benefits and uses

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This process is a multifaceted and intricate regulatory mechanism, with multiple pathways mediating mitophagy demonstrating parallelism or redundancy to preserve the equilibrium between mitochondrial homeostasis and the mitochondrial quality control system (Figure 3)

A WHO consultation identified the most vulnerable groups as elderly individuals, infants, preschool-aged children, and pregnant or lactating women, due to either increased nutritional demands or impaired absorption capacity ( Addressing the prevention of B12 deficiency and its public health implications requires a comprehensive, life-course approach based on integrated strategies targeting early detection, dietary optimisation, and effective supplementation, in order to mitigate the long-term consequences of inadequate cobalamin status (Organization, 2000)