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and disrupted synthesis and release of neurotransmitters such as dopamine, serotonin, and NE, directly promoting anxiety-like behaviors [460]

Promote cell proliferation and inhibit apoptosis The E-P-OS network activates pro-survival and proliferation pathways such as PI3 K/Akt/mTOR, leading to the overexpression of Cyclin D1, c-Myc, PCNA, and Ki67 in uterine fibroid cells

The review also assesses the current level of technological readiness of hydrogen-assisted extraction, identifies key knowledge gaps, and considers the conditions required for its safe and practical implementation