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Because the redox states of these Cys thiols are regulated by the activity of thioredoxin (TRX) and GSH enzymatic systems and by the reductive power of NADPH (Fig
and these observations may correspond to seasonal changes in solar insolation, alterations in melatonin production and seasonal influence on the hypothalamicpituitarythyroid (HPT) axis, especially at locations of increasing distance from the equator [353]
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