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They are water-soluble which just means that if there's anything in excess, it will be just excreted through urine or bile
Monteiro CA, Moubarac JC, Levy RB, Canella DS, Louzada MLDC, Cannon G (2018) Household availability of ultra-processed foods and obesity in nineteen European countries

N Engl J Med 310 : 810815 Baxter RC (1995) Insulin-like growth factor binding proteins as glucoregulators

Evidence is indicating these conditions may be comorbid with long COVID as well