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doi: 10.1016/j.jaad.2009.09.018

Abstract Multiple sclerosis (MS) is an autoimmune disease characterized by demyelination and axonal loss of the central nervous system (CNS)

There were no group differences in BMI, hematocrit and hemoglobin concentrations, renal functions, or liver enzymes

In patients taking opioids for an extended period of time at high doses, ensure that a multimodal approach to pain management, including mental health support (if needed), is in place prior to initiating an opioid analgesic taper [seeDOSAGE AND ADMINISTRATION,and WARNINGS]
