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Description
3 Current Pharmaceutical Design (PMC)Sikiric P et al
Begin within days of surgery continuing through rehabilitation phase (3-6 months typically)

Evidence showed, as mentioned, wide therapy counteracting potential (NO-release, NO-synthase (NOS)-inhibition (L-NAME), NOS-over-activity (L-arginine), NO-system immobilization (L-NAME+L-arginine)

Individual circumstances: While guidelines are in place, a doctor is ultimately responsible for making decisions appropriate for each patient
