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The insulin and cytokine network

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U samom transportu sudjeluju 4 enzima koji se nalaze na membranama mitohondrija pa unos masnih kiselina ovisi i o njima

While these observations suggest benefit, given that L-T4 has a narrow toxic-to-therapeutic window, and iatrogenic thyrotoxicosis and/or unwarranted treatment may theoretically lead to complications (i.e., increased protein catabolism, reduced bone mineral density, arrhythmia) rigorous longitudinal studies and randomized controlled trials are needed to provide more definitive information on the safety and effectiveness of exogenous thyroid hormone supplementation in hypothyroid CKD patients