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Description
The observed sustained release of NC-CUR holds significant therapeutic potential, enabling more stable plasma concentrations over time, which may reduce the need for frequent dosing and minimize concentration spikes that could lead to adverse effects (Tiatragoon et al., 2024)

doi: 10.3390/ijms241310858 173 ThakurKZhuY-YFengJ-YZhangJ-GHuFPrasadCet al

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In turn, HSF-1 homotrimerizes and is sent to the nucleus, where, connecting to the regulatory heat shock elements (HSE) in the promoter regions of DNA, it starts the process of transcription of Hsp genes
