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10.1126/science.aaa2361 [DOI] [PMC free article] [PubMed] [Google Scholar] 46.Shokr H, Dias IH, Gherghel D
However, given that the course of the disease is influenced by the interplay of individual factors, a comprehensive and personalized approach is essential in managing treatment
It should be noted that besides BACE-1, a close homolog BACE-2 is also identified but there is no clear evidence relating any cleavage activities of this secretase in human APP protein
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