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In addition, donepezil (1 mg/kg, p.o., five times per week for 4 weeks) could ameliorate OXA-induced mechanical allodynia and sciatic nerve axonal degeneration in a rat model, whose neuroprotective effect was attributed to its free-radical scavenging ability (Kawashiri et al., 2019)

Moreover, resistin has been suggested to aggravate hepatic inflammation and fibrosis by enhancing the production of pro-inflammatory cytokines [217]

The positive transformants were screened by PCR and plasmids were extracted using a TaKaRa MiniBEST Plasmid Purification Kit (Takara, Dalian, China)

Long-term benefits include ongoing immune health and detoxification