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Residual TrxR1 in the tissue lysate is likely derived from non-hepatocyte cell types such as endothelia, as shown previously with conditional TrxR1-knockout livers 10,20,23
doi: 10.1016/j.foodhyd.2021.107367 [DOI] [Google Scholar] 58.Cui H, Cheng Q, Li C, Chen X, Lin L
Lars Nielsen about this issue, he advised us that even when we have more than one measurement for the same organism, the values can vary many fold (Km) to several orders (kcat)
Front Immunol 9(8):521
