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doi: 10.1074/mcp.M700085-MCP200 82 McLaughlinRJde HaanAZaldumbideAde KoningEJde RuAHvan VeelenPAet al
The consistent significant difference in weight loss outcomes between the tesofensine and placebo groups, especially in phase III trials, reinforces the drug's robust efficacy and potential for addressing the challenges of obesity treatment
Similarly, a study demonstrated that pro-apoptotic markers (p53, p21, Bax, and caspase-3) stained positive in type II AECs from IPF subjects, while anti-apoptotic markers (Bcl-2) exhibited reduced expression compared to control subjects (100)
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