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Description
NF-B is negatively regulated via S -glutathionylation, which is overcome by glutaredoxin-1 (GRX1), the latter under physiological conditions catalyzes deglutathionylation and enhances NF-B activation [73]
More research is neededbut only if it is good research

Ethics declarations Competing interests KGW and VJNB are co-founders and shareholders of Aprea Therapeutics AB, a company that develops novel p53-based cancer therapy
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Clin Cancer Res 23, 10121024 (2017)
