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Effect of Diindolylmethane on Estrogen-related Hormones, Metabolites and Tamoxifen Metabolism: Results of a Randomized, Placebo-controlled Trial

This is especially important for patients taking warfarin or other anticoagulants, who should consult their anticoagulation clinic before starting or stopping these supplements
Bartholomae E, Knurick J, Johnston CS

As always, it's recommended to consult a healthcare professional before starting any new supplement, to ensure it's suitable for your personal needs and goals
