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Savitikadi, P., et al

Phase I study of mitoxantrone plus etoposide with multidrug blockade by SDZ PSC-833 in relapsed or refractory acute myelogenous leukemia

Birth Defects Res A
Increased ROS levels are thought to have an oncogenic effect, inducing DNA damage and chromosomal instability to activate proto-oncogenes and inactivate tumor suppressor genes (12, 13)
