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Downstream DAMP-associated microglia activation results in the assembly of the classical NADPH oxidase on the plasma membrane, resulting in the release of superoxides into the extracellular space, where they contribute to neuronal damage (Della Bianca et al., 1999)
As discussed earlier, sperm consists of an array of cytokines and immune factors, although their effect on semen quality and sperm function parameters needs to be debated (81, 82)
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