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2016;70(11):1340.doi:10.1038/ejcn.2016.78 Sarma DN, Barrett ML, Chavez ML, etal

Impairment of the energy metabolism of the mitochondrion is said to be involved in migraine pathogenesis

Dysfunction in the gut barrier (intestinal hyperpermeability or leaky gut) appears in most autoimmune conditions, potentially serving as both a trigger for initial autoimmune development and a perpetuating factor that maintains immune dysregulation
Congenital Vitamin E deficiency
