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In rabbits fed on HCD, BBB tight junction proteins expression was down-regulation and IgG was increased in the hippocampus, suggesting that BBB is disrupted because IgG is not present in normal brain parenchyma (Jiang et al., 2012)
possesses neuroprotective properties and is able to boost new nerve networks structural formation (Sedighi et al., 2014
Gomase et al., 2025)
The importance of the NRF2 system in Alzheimers disease has been documented by the fact that impairment of NRF2 in mouse models resulted in deteriorated cognitive abilities (Perluigi et al
