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On the basis of the gold score, it is noted that most of the carcinogens/toxins bind almost equally with both wild and mutant GSTP1, except for gallotanic acid, a derivative of RAN, showed better binding with GSTP1 GG-genotype (Table 4), whereas N-nitrosonornicotine (NNN), a derivative of tobacco, showed better binding with GSTP1 AA-genotype (Table S6)

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Therefore, the replacement of folic acid with 5-methyl-THF in prenatal vitamins should be strongly considered as universally beneficial

Pregnant or breastfeeding women should talk to their doctor before getting B12 injections