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In some embodiments, the otic formulation or composition comprises about 15% by weight of the cholesterol

The contribution of ACSL4 to ferroptosis hinges on its ability to attach CoA moieties to long-chain PUFAs, after which LPCAT3 or related enzymes esterify these long-chain PUFAs into lysophospholipids

Live-cell imaging of oROS-G in primary cultured mouse astrocytes On DIV7, primary cultured astrocytes were transfected with AAV5-GFAP-oROS-GFP viral vector and seeded into a glass-bottom 96-well plate (ibidi

Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S -glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells