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Even though GSH levels were below the threshold for rescuing WT cell growth in cystine-free conditions, co-culturing with GGT1 + cells led to complete rescue of WT cell growth (Fig
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This process is known as genomic or nuclear response and entails up- and down-regulation of diverse genes associated with cell proliferation, survival, and migration (Musgrove and Sutherland, 2009
The MOTS-c peptide , encoded in mitochondrial DNA, has therefore been investigated as a potential tool for extending healthspan and delaying age-related decline
