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Alpha-Lipoic Acid Applications It is known that ALA affects carbohydrate and lipid metabolism [56,57], regulates appetite [58], fights complications of diabetic origin [59] and myocardial and cerebral reperfusion injuries [60], supports the therapy of neurodegenerative diseases [61], and activates apoptosis in tumor cell lines [62]

doi: 10.1016/s0022-3476(98)70228-8
The human heart derives up to 70% of its total energy from the beta-oxidation of fatty acids, making the myocardium exquisitely sensitive to carnitine depletion
