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doi: 10.1111/j.1468-3083.2010.03638.x
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The ROS produced by mitochondria can accelerate the oxidation of polyunsaturated fatty acids in the cell membrane lipids, a process known as lipid peroxidation (LPO) that changes the cell membrane structure, impairing its integrity, thus affecting cell signaling
Targeting GLN metabolism in cancer cells without interfering with the immune response is a major challenge for future research
