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(5) Thus, it is believed that Sermorelin may retain the core ability of GHRH: to potentially prompt the GHRH receptors in the pituitary gland to intermittently release growth hormone

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Z 1 is H, (C 1 -C 5 ) alkyl, or phenyl optionally substituted with one, two, or three groups of (C 1 -C5) alkyl, (C 1 -C5) alkoxy, (C 1 -C 4 ) thioalkoxy, halogen, nitro, COOR, ONHR, -O(CH 2 ) n COOR, -S(CH 2 ) n COOR, -O(CH 2 ) n CONHR, or - S(CH 2 ) n CONHR wherein n and R are as defined above