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Administration of lesion targeting nanoparticles containing the bioactive annexin 1 peptide, Ac2-26, to Ldlr -/- mice with atherosclerosis reduced both lesional oxidative stress and necrosis while increasing collagen content and fibrous cap thickness (213)

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Combining medication or supplements that jointly boost serotonin can cause it to accumulate and reach abnormally high levels in the body - a serious condition called serotonin syndrome, which can result in shivering, diarrhea, muscle rigidity, fever or seizures

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