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Graves orbitopathy is the most relevant extrathyroid manifestation [10,16]

This intervention led to clinically meaningful improvements in fatigue, sleep quality, and functional well-being without any adverse events, further supporting the safety and acceptability of exercise during active treatment [228]

The most recent version indicates that low-carbohydrate and very-low-carbohydrate diets lead to reductions in HbA1c levels and support dosage reductions of glucose-lowering medications in T2DM patients [173]

Fluorescent staining was visualized and images were acquired with a 63x oil immersion objective (NA = 1.2) with a 2x optical zoom on a Leica Stellaris 5 White Light Laser Confocal Microscope coupled to a camera integrated with LasX software for Lightning deconvolution (Leica Biosystems, Deer Park, IL, USA)