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Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells
Kimball et al
Furthermore, the maximum rate of exchange occurs when the pH is high, and its value exponentially increases with the increase in the pKa of the imidazole ring itself ( Another interesting class of carbon atoms that may serve as deuterium traps are the bis-allylic carbon atoms, notably present in both microbial breakdown products of haem and in polyunsaturated fatty acids (PUFAs)
doi: 10.1007/s00344-020-10152-x
