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Network toxicological analysis To assess PFAS toxicity, we used ProTox-3.0 ( and ADMETlab 2.0 ( PubChem ( was used to download structure files and the simplified molecular input line entry system (SMILES) numbers for PFAS mixtures (PFOS, PFOA, PFNA, PFHxS) and folate forms (Tetrahydrofolate, 5-Methyltetrahydro Tetrahydro folate, 5,10-Methylenetetrahydro Tetrahydro folate) that exert important physiological functions [50]
mTOR signaling: new insights into cancer, cardiovascular diseases, diabetes and aging
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doi: 10.1126/science.2849206
