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Firstly, the methodological quality of included studies was less than optimal, so we were not able to exclude the potential risk of bias in these trials

DOX has been linked to the production and accumulation of ROS in the mitochondria, which can damage mitochondrial DNA and impair the activity of the mitochondria 87

A suplementao de L-Carnitina pode aumentar o fluxo sanguneo aos msculos devido tambm ao seu efeito vasodilatador e antioxidante, reduzindo algumas complicaes de doenas isqumicas, como a doena arterial coronariana e as consequncias da neuropatia diabtica

Pooyandjoo, M., et al
