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Do I need a blood test before getting a B12 injection

Circulating levels of tumour necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis
Cytology is important to rule out lymphoma and decrease the odds of significant neutrophilic inflammation, but histopathology may be needed for definitive diagnosis and an optimal long-term treatment plan

However, a higher amount may be required initially to observe a therapeutic effect