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doi: 10.1021/bi961801a

Impairment of Other Metabolic Processes Chronic ethanol consumption and alcohol metabolism also may influence various other metabolic pathways, thereby contributing to metabolic disorders frequently found in alcoholics, such as fatty liver and excessive levels of lipids in the blood (i.e., hyperlipidemia), accumulation of lactic acid in the body fluids (i.e., lactic acidosis), excessive production of chemical compounds known as ketones in the body (i.e., ketosis), and elevated levels of uric acid in the blood (i.e., hyperuricemia)

Special populations Certain groups should exercise caution when taking vitamin B12 supplements: Pregnant and breastfeeding women : Vitamin B12 is required during pregnancy and breastfeeding to prevent cognitive and developmental delays, but taking only the recommended amounts is essential

Both protein kinase B (AKT) and DNA damage-inducing transcript 4 (DDIT4) are mammalian target of rapamycin (mTOR) regulators, which play an important role in the regulation of autophagy 35,36